Debridement and Infection Management

1. Debridement

Debridement is the removal of nonviable tissue, foreign material, and biofilm from a wound to create an optimal healing environment.

Goals of Debridement

  • Reduce bacterial load and biofilm

  • Stimulate wound healing

  • Improve effectiveness of topical therapies

  • Allow accurate wound assessment

Types of Debridement

 

1. Sharp/Surgical Debridement
  • Performed with scalpel, scissors, or curette

  • Fastest and most effective method

  • Indicated for infected, necrotic, or rapidly deteriorating wounds

  • Requires trained clinician and appropriate pain control

2. Mechanical Debridement
  • Wet-to-dry dressings, wound irrigation

  • Non-selective (removes healthy tissue as well)

  • Less commonly recommended today

3. Autolytic Debridement
  • Uses moisture-retentive dressings (hydrocolloids, hydrogels)

  • Selective and painless

  • Best for stable, non-infected wounds

4. Enzymatic Debridement
  • Topical enzymes (e.g., collagenase)

  • Selective and useful when sharp debridement is not appropriate

5. Biological Debridement
  • Medical-grade maggots

  • Highly selective and effective for resistant necrotic tissue

2. Infection Management

Wound infection occurs when bacterial burden overwhelms the host’s defenses, delaying healing.

Signs of Wound Infection

 

Local Signs
  • Increased pain

  • Erythema, warmth, edema

  • Purulent drainage

  • Malodor

  • Friable granulation tissue

Systemic Signs
  • Fever or chills

  • Elevated WBC

  • Hyperglycemia (especially in diabetic patients)

  • Delayed healing

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